Biocare Products
Biocare Medical Double Vision Detection

Biocare Medical Multiplex Stains
Stains for multiple antibodies on a single slide

Biocare Medical Double Vision Multiple Stain System

Using the Multiplex staining system you can achieve remarkable multiple stain results like never seen before.

° Reduces the number of steps from 12-16 to 4-7 steps
° Avoids endogenous biotin blocking
° Processes 50+ percent less slides
° Has a turnaround time of less than two hours (4-step procedure)
° Is compatible with either manual or automated systems
° Needs less slides for interpretation

This new and innovative alkaline phosphatase (AP) and horseradish peroxidase (HRP) polymerization technology provides a significant increase in staining sensitivity when compared to other conventional AP or HRP conjugated secondary antibodies. It has been specially designed for a rapid double stain procedure and is suitable for most IHC automated stainers.

Biocare multiplex chromogenic and fluorescent systems are validated for multispectral imaging and image analysis. Click here for more information on CRi Nuance™ Multispectral Imaging systems.

Polymer Detection Kit #1 (4-Step)
(Mouse AP + Rabbit HRP)

Cat. No. Vol.
MRCT523G, H, L 6.0, 25, 100 ml

Polymer Detection Kit #2 (4-Step)
(Mouse HRP + Rabbit AP)

Cat. No. Vol.
MRCT525G, H, L 6.0, 25, 100 ml

MACH 2 Mouse Kits (for 7-Step)

Cat. No. Vol.
MHRP520 + MALP521 G, H, 6.0, 25 ml

Denaturing Solution
The 7-step kit is provided with a Denaturing Solution which prevents the second staining protocol from cross-reacting with the first. Denaturing Solution can also be purchased separately.

Cat. No. Vol.
DNS001H, L 25, 100 ml


Multiplex Stain Antibodies

Name Cat. No. DATA SHEET Protocol / Kit
CD10 + Cyclin D1 PM314DSAA DATA SHEET Kit #1
CD23 + CD5 PM315DSAA DATA SHEET Kit #1
CD56 + Synaptophysin PPM316DSAA DATA SHEET Kit #2
CDX2 + CK7 PPM338DSAA DATA SHEET Kit #2
CK5 + p63 with CK8/18 PM228DSAA DATA SHEET MACH 2 Mouse
CK5/6 + Calretinin PM246DSAA DATA SHEET Kit #2
D2-40 and CD34 PM272DSAA DATA SHEET MACH 2 Mouse
GCDFP-15 + Mammaglobin PM317DSAA DATA SHEET Kit #2
HMW CK and LMW CK PM245DSAA DATA SHEET MACH 2 Mouse (7 step)
Ki-67 + Caspase-3 PPM240DSAA DATA SHEET Kit #2
Kappa + Lambda PPM214DSAA DATA SHEET Kit #2
L26 + CD3 PM237DSAA DATA SHEET Kit #1
Pan Melanoma + S100 (Tyrosinase + MART-1 + S100 ) PPM213DSAA DATA SHEET Kit #2
PIN-4 Cocktail (CK5 + CK14 + p63 + P504S) PPM225DSAA ASR / RUO Kit #2

For more comprehensive information about Multiplex Stain Antibodies, see the antibody section of this website.